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3D Printing Technology Is Used For The First Time To Treat Femoral Head

Jul 03, 2020

Recently, a team of professor Guo Zheng from the Department of Orthopaedics, Xijing Hospital, Air Force Military Medical University, successfully implanted titanium alloy support rods with a graduated human bone structure into patients with femoral head necrosis, which can effectively relieve pain symptoms and improve joint function. According to the retrieval, the clinical use of 3D printed bionic porous support rods to treat femoral head necrosis is the first in the world.

The incidence of femoral head necrosis is high

Femoral head necrosis is one of the common and refractory chronic diseases in orthopaedics. According to incomplete statistics, there are currently about 30 million patients with femoral head necrosis worldwide, and about 4 million people in China. Most of the early manifestations of the disease are hidden pain around the hip joint and increased after activity. Further development can lead to the collapse of the femoral head, and eventually the artificial joint can only be replaced. In the early and middle stages of femoral head necrosis, clinical intervention to delay or prevent the collapse of the femoral head is an important measure for hip preservation.

In the past, the main intervention method for early and mid-term patients was to decompress the femoral head. Although simple decompression can relieve the pain symptoms, due to the lack of mechanical support in the necrotic area, it may accelerate the femoral head collapse. Currently, porous tantalum rods are used for support internationally, but the therapeutic effect of porous tantalum rods has certain limitations.

8 years of innovation and research and development of femoral head support rods

In view of the extremely critical treatment characteristics of early and mid-term femoral head necrosis intervention, since 2010, Professor Guo Zheng’s team has carried out research on early and mid-term treatment of femoral head necrosis, in 1 national key research and development, 2 national 863 plans and 4 national natural science funds With funding, we successfully established a stable animal model of femoral head necrosis, and developed more than ten kinds of support rods with different configurations and different materials. We obtained 4 national invention patents and published 11 related researches on porous support rods in international authoritative magazines.

The support rod developed by Professor Guo Zheng's team innovatively adopts the design of the gradient imitation human bone structure and the central pipeline. The gradient imitation human bone structure design can replace or share the weight bearing function of the femoral head, so that the patient can avoid the collapse of the femoral head under normal walking conditions. It is conducive to the growth of bone tissue and is closely combined with surrounding bones to increase mechanical properties. The central pipeline design can be used as a channel to maintain the core decompression, as well as a channel for injection of artificial bone or other bone-inducing active substances, so that the injected artificial bone or bone-inducing drugs are distributed to the area of femoral head necrosis and promote new bone formation. , To repair the necrotic area.

In vivo implantation of 3D printed support rods Minimally invasive precision treatment of femoral head necrosis

42-year-old Li Wei (pseudonym) from Yulin, Shaanxi Province, suffered from left hip pain 6 months ago, which was significantly worse when he squatted or tired. After coming to Xijing Hospital, the diagnosis was confirmed as bilateral femoral head necrosis. After consultation, the expert team decided to apply a series of innovative results and implanted titanium alloy femoral head support rods that mimic the human bone structure.

Before the operation, the Department of Orthopedics of Xijing Hospital, Xi’an Dimension Biotechnology and Shaanxi Dongwang Technology jointly designed, based on the image data of the femoral head necrosis area, through digital personalized design, 3D printed titanium alloy femoral head support rods imitating human bone structure. According to Professor Fan Hongbin, the chief surgeon of this operation, the entire operation was minimally invasive and the implantation process was smooth. It took only 30 minutes to avoid joint replacement, realized minimally invasive precision operation, and saved surgical costs. On the day of the operation, the patient's pain around the hip joint was significantly relieved, and the joint function recovered satisfactorily a week after the operation.

It is reported that the 3D printed human bone titanium alloy femoral head support rod has been awarded a national invention patent, which provides a new solution for the treatment of femoral head necrosis and is expected to benefit more patients with femoral head necrosis in the near future.